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Image Search Results
Journal: Molecular Cytogenetics
Article Title: Analytical validation and chromosomal distribution of regions of homozygosity by oligonucleotide array comparative genomic hybridization from normal prenatal and postnatal case series
doi: 10.1186/s13039-019-0424-6
Figure Lengend Snippet: SNP calling failure rate in association with DLR. SNP calling data were extracted from a . Agilent 180 K aCGH/SNP array, and b . Agilent 400 K aCGH/SNP array. SNP calling failure rate increased significantly when DLR is greater than 0.2 (**, p < 0.01). No significant difference (NS) between samples of DLR 0.2–0.3 and DLR > 0.3
Article Snippet: SNP calling data were extracted from a .
Techniques:
Journal: Redox Biology
Article Title: BRCA1 haploinsufficiency promotes chromosomal amplification under Fenton reaction-based carcinogenesis through ferroptosis-resistance
doi: 10.1016/j.redox.2022.102356
Figure Lengend Snippet: Expression microarray analysis at the subacute phase of Fe-NTA-induced renal carcinogenesis sorts out mitochondrial and iron metabolisms as candidate responsible pathways in Brca1 MUT(L63X/+) rat. (A) Results of hierarchical clustering and GO term analysis for the genes differentially expressed between WT and Brca1 MUT at 3 weeks in the Fe-NTA-induced renal carcinogenesis protocol (refer to ). (B) Renal Brca1 expression during the subacute phase of Fe-NTA-induced renal carcinogenesis protocol with qPCR (left panel; means ± SD) and immunoblot analysis (right panels). (C) Examples of altered metabolisms and mitochondrial dysfunction with expression microarray analysis specifically in the kidney of Brca1 MUT rats during the subacute phase of Fe-NTA-induced renal carcinogenesis (n = 3; * P < 0.05, ** P < 0.01, *** P < 0.001 vs wild-type Fe-NTA renal carcinogenesis protocol at 3 weeks). Refer to text for details.
Article Snippet: We labeled DNA from 16 rat primary RCCs (4 in wild-type without metastasis, 4 in wild-type with pulmonary metastasis, 4 in Brca1-MUT rat without metastasis, and 4 in Brca1-MUT rat with pulmonary metastasis; randomly selected from RCC samples of appropriate size [diameter >15 mm] without massive necrosis and obtained by scheduled autopsy; ) with Cy-5 and the corresponding control DNA with Cy-3, which were applied to the
Techniques: Expressing, Microarray, Western Blot